Aporphine and phenanthrene alkaloids with antioxidant activity from the roots of Stephania tetrandra
R Wang, J Zhou, G Shi, Y Liu, D Yu - Fitoterapia, 2020 - Elsevier
Abstract Five new alkaloids (1–5), including three new aporphine alkaloids and two new
phenanthrene alkaloids, together with 10 known compounds (6–15) were obtained from the
roots of Stephania tetrandra. Their structures were elucidated by spectroscopic methods,
single-crystal X-ray diffraction, and electronic circular dichroism analyses. Compounds 7–
10, and 13 showed antioxidant activities with malondialdehyde (MDA) inhibitory rates of
62.50±1.91 to 98.44±0.34% at the concentration of 10 μM.
phenanthrene alkaloids, together with 10 known compounds (6–15) were obtained from the
roots of Stephania tetrandra. Their structures were elucidated by spectroscopic methods,
single-crystal X-ray diffraction, and electronic circular dichroism analyses. Compounds 7–
10, and 13 showed antioxidant activities with malondialdehyde (MDA) inhibitory rates of
62.50±1.91 to 98.44±0.34% at the concentration of 10 μM.
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